Once you do them they completely change you…… It has to do with the nervous system, ingredients, stuff like that. The drugs tell your brain, " You need to keep this up!! This is awesome…" your brain tells the rest of your body, " This is what we need to be doing it is good for us!!" Well it isn't…… It can affect you in so many different ways besides the brain….
They affect the brain in a very large variety and degree of ways. It's hard to say for all of those, however I'll firstly do stimulants, as they are my specialty. Stimulants, such as Amphetamine (Adderall), Methamphetamine (Both street grade and dextroamphetamine), or Methylphenidate (Ritalin) affect the brain by several ways. Firstly, it increases the level of dopamine in the brain, through the receptor l-dopa. This will create a general feeling of confidence, increased desire of activity, and overall happy feelings. It will also increase the level of Serotonin in the brain. It will further it's affects of stimulation by causing basic malfunction of brain synapse response and communication, temporarily causing more rapid affect and furthering possibility of malfunction and neural damage. This is through affecting Noreprenephrine (spelling?). Hope I helped some, Mini
They are all different. Some uppers (stimulants) can make your chemical serotonin release a lot! thus making you happy and feeling like you can go a mile a minute. Depressants make people feel high. Pain medications make people high too. They make your thinking groggy, they make you feel heavy. They make you hot. Make people mean. Basically here is your answer. Any drug will change the level of chemical's in your body/brain. Every drug will change your brain in a different way, only if it is temporary.